Thursday, May 9, 2013

Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells

Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells:



Casey A. Gifford, Michael J. Ziller, Hongcang Gu, Cole Trapnell, Julie Donaghey, Alexander Tsankov, Alex K. Shalek, David R. Kelley, Alexander A. Shishkin, Robbyn Issner, Xiaolan Zhang, Michael Coyne, Jennifer L. Fostel, Laurie Holmes, Jim Meldrim, Mitchell Guttman, Charles Epstein, Hongkun Park, Oliver Kohlbacher, John Rinn, Andreas Gnirke, Eric S. Lander, Bradley E. Bernstein, Alexander Meissner. Differentiation of human embryonic stem cells (hESCs) provides a unique opportunity to study the regulatory mechanisms that facilitate cellular transitions in a human context. To that end, we perf....

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