Tuesday, May 7, 2013

FACT action during chromatin transcription [Biochemistry]

FACT action during chromatin transcription [Biochemistry]: FACT (facilitates chromatin transcription) is a histone chaperone that promotes chromatin recovery during transcription, with additional roles in cell differentiation. Although several models of the action of FACT during transcription have been proposed, they remain to be experimentally evaluated. Here we show that human FACT (hFACT) facilitates transcription through chromatin...

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