Friday, May 17, 2013

Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data

Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data:
Nature Reviews Genetics 14, 390 (2013).
doi:10.1038/nrg3454

Authors: Job Dekker, Marc A. Marti-Renom & Leonid A. Mirny
How DNA is organized in three dimensions inside the cell nucleus and how this affects the ways in which cells access, read and interpret genetic information are among the longest standing questions in cell biology. Using newly developed molecular, genomic and computational approaches based on

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