Thursday, May 23, 2013

Paused Pol II Coordinates Tissue Morphogenesis in the Drosophila Embryo

Paused Pol II Coordinates Tissue Morphogenesis in the Drosophila Embryo: Mounia Lagha, Jacques P. Bothma, Emilia Esposito, Samuel Ng, Laura Stefanik, Chiahao Tsui, Jeffrey Johnston, Kai Chen, David S. Gilmour, Julia Zeitlinger, Michael S. Levine.

Paused RNA polymerase (Pol II) is a pervasive feature of Drosophila embryos and mammalian stem cells, but its role in development is uncertain. Here, we demonstrate that a spectrum of pause....

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