Wednesday, June 27, 2012

A map of nucleosome positions in yeast at base-pair resolution

A map of nucleosome positions in yeast at base-pair resolution:
A map of nucleosome positions in yeast at base-pair resolution

Nature 486, 7404 (2012). doi:10.1038/nature11142

Authors: Kristin Brogaard, Liqun Xi, Ji-Ping Wang & Jonathan Widom
The exact positions of nucleosomes along genomic DNA can influence many aspects of chromosome function. However, existing methods for mapping nucleosomes do not provide the necessary single-base-pair accuracy to determine these positions. Here we develop and apply a new approach for direct mapping of nucleosome

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