DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina

DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina: Joseph M. Zullo, Ignacio A. Demarco, Roger Piqué-Regi, Daniel J. Gaffney, Charles B. Epstein, Chauncey J. Spooner, Teresa R. Luperchio, Bradley E. Bernstein, Jonathan K. Pritchard, Karen L. Reddy, Harinder Singh. A large fraction of the mammalian genome is organized into inactive chromosomal domains along the nuclear lamina. The mechanism by which these lamina associated domains (LADs) are established rema....