Genomic approaches towards finding cis-regulatory modules in animals
Nature Reviews Genetics 13, 469 (2012).
doi:10.1038/nrg3242
Authors: Ross C. Hardison & James Taylor
Differential gene expression is the fundamental mechanism underlying animal development and cell differentiation. However, it is a challenge to identify comprehensively and accurately the DNA sequences that are required to regulate gene expression: namely, cis-regulatory modules (CRMs). Three major features, either singly or in
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