Splicing: Waiting to be spliced

Splicing: Waiting to be spliced:
Splicing: Waiting to be spliced

Nature Reviews Genetics 13, 599 (2012).
doi:10.1038/nrg3310

Author: Hannah Stower
The relevance of co-transcriptional versus post-transcriptional splicing of transcripts is debated. In a recent RNA sequencing (RNA-seq) study of the human inflammatory response, the authors found evidence for the widespread association of incompletely spliced transcripts with chromatin. Thus, this study supports post-transcriptional rather than co-transcriptional