Rate of de novo mutations and the importance of father’s age to disease risk
Nature 488, 7412 (2012). doi:10.1038/nature11396
Authors: Augustine Kong, Michael L. Frigge, Gisli Masson, Soren Besenbacher, Patrick Sulem, Gisli Magnusson, Sigurjon A. Gudjonsson, Asgeir Sigurdsson, Aslaug Jonasdottir, Adalbjorg Jonasdottir, Wendy S. W. Wong, Gunnar Sigurdsson, G. Bragi Walters, Stacy Steinberg, Hannes Helgason, Gudmar Thorleifsson, Daniel F. Gudbjartsson, Agnar Helgason, Olafur Th. Magnusson, Unnur Thorsteinsdottir & Kari Stefansson
Mutations generate sequence diversity and provide a substrate for selection. The rate of de novo mutations is therefore of major importance to evolution. Here we conduct a study of genome-wide mutation rates by sequencing the entire genomes of 78 Icelandic parent–offspring trios at high
Genome Evolves By Culture, Natural Selection, Not Randomly
ReplyDeleteTags: genetic mutations, RNAs are organisms,
A.
Rate of de novo mutations and the importance of father’s age to disease risk
http://www.nature.com/nature/journal/v488/n7412/full/nature11396.html
B.
RNA nucleotide genes are ORGANISMS, life’s primal ORGANISMS.
Genomes are template ORGANISMS evolved by the RNAs for carrying out their - RNAs’ - natural-selection tasks.
All life’s activities originate and evolve for the survival of the RNAs.
THIS is Darwinian evolution.
C.
Modified RNAs expressions are NOT random mutations. Some of them are caused accidents, but not random. Apply Darwinism to them.
There is no randomness in the universe that evolves from all inert mass, singularity, to all moving mass, energy, and probably back again.
Now, after a century of strangled Enlightenment, it’s time to restructure science plans, policies and budgets.
The viable future of humanity is not with natural selection, but with scientism, the follow up of Enlightenment.
Dov Henis (comments from 22nd century)
http://universe-life.com/