Friday, December 9, 2011

Polycomb-Repressed Genes Have Permissive Enhancers that Initiate Reprogramming

Polycomb-Repressed Genes Have Permissive Enhancers that Initiate Reprogramming: Phillippa C. Taberlay, Theresa K. Kelly, Chun-Chi Liu, Jueng Soo You, Daniel D. De Carvalho, Tina B. Miranda, Xianghong J. Zhou, Gangning Liang, Peter A. Jones. Key regulatory genes, suppressed by Polycomb and H3K27me3, become active during normal differentiation and induced reprogramming. Using the well-characterized enhancer/promoter pair of MYOD1</i....

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