Friday, July 26, 2013

Local features determine cis-regulatory function [Genetics]

by White, M. A., Myers, C. A., Corbo, J. C., Cohen, B. A.
Transcription factors (TFs) recognize short sequence motifs that are present in millions of copies in large eukaryotic genomes. TFsmust distinguish their target binding sites from a vast genomic excess of spurious motif occurrences; however, it is unclear whether functional sites are distinguished from nonfunctional motifs by local primary sequence features...

No comments:

Post a Comment