Friday, July 26, 2013

DNA-binding site changes in forkhead evolution [Evolution]

DNA-binding site changes in forkhead evolution [Evolution]

by Nakagawa, S., Gisselbrecht, S. S., Rogers, J. M., Hartl, D. L., Bulyk, M. L.
The evolution of transcriptional regulatory networks entails the expansion and diversification of transcription factor (TF) families. The forkhead family of TFs, defined by a highly conserved winged helix DNA-binding domain (DBD), has diverged into dozens of subfamilies in animals, fungi, and related protists. We have used a combination of maximum-likelihood...

No comments:

Post a Comment