Spatial Organization of the Mouse Genome and Its Role in Recurrent Chromosomal Translocations

Spatial Organization of the Mouse Genome and Its Role in Recurrent Chromosomal Translocations: Yu Zhang, Rachel Patton McCord, Yu-Jui Ho, Bryan R. Lajoie, Dominic G. Hildebrand, Aline C. Simon, Michael S. Becker, Frederick W. Alt, Job Dekker. The extent to which the three-dimensional organization of the genome contributes to chromosomal translocations is an important question in cancer genomics. We generated a high-resolution Hi-C spat....