Thursday, May 5, 2011

Mapping and analysis of chromatin state dynamics in nine human cell types

Mapping and analysis of chromatin state dynamics in nine human cell types: "


Mapping and analysis of chromatin state dynamics in nine human cell types


Nature 473, 7345 (2011). doi:10.1038/nature09906


Authors: Jason Ernst, Pouya Kheradpour, Tarjei S. Mikkelsen, Noam Shoresh, Lucas D. Ward, Charles B. Epstein, Xiaolan Zhang, Li Wang, Robbyn Issner, Michael Coyne, Manching Ku, Timothy Durham, Manolis Kellis & Bradley E. Bernstein


Chromatin profiling has emerged as a powerful means of genome annotation and detection of regulatory activity. The approach is especially well suited to the characterization of non-coding portions of the genome, which critically contribute to cellular phenotypes yet remain largely uncharted. Here we map nine


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