Enhancer function: new insights into the regulation of tissue-specific gene expression

Enhancer function: new insights into the regulation of tissue-specific gene expression: "

Enhancer function: new insights into the regulation of tissue-specific gene expression

Nature Reviews Genetics 12, 283 (2011). doi:10.1038/nrg2957

Authors: Chin-Tong Ong & Victor G. Corces

Enhancer function underlies regulatory processes by which cells establish patterns of gene expression. Recent results suggest that many enhancers are specified by particular chromatin marks in pluripotent cells, which may be modified later in development to alter patterns of gene expression and cell differentiation choices.

"