Tuesday, June 18, 2013

Gene regulation: mRNA decay factors regulate transcription

Gene regulation: mRNA decay factors regulate transcription:
Nature Reviews Genetics 14, 444 (2013).
doi:10.1038/nrg3530

Author: Mary Muers
Levels of mRNAs depend on the balance of their synthesis and decay; this study reveals a way in which the two processes are intimately connected. Working in yeast, Haimovich et al. found that components of the cytoplasmic 5′ to 3′ decay pathway (collectively known

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