Monday, March 18, 2013

Gene expression: Influences on noise

Gene expression: Influences on noise:
Nature Reviews Genetics 14, 238 (2013).
doi:10.1038/nrg3448

Author: Mary Muers
Studies of transcription at a single-cell level have revealed extensive cell-to-cell variability in gene expression levels: a phenomenon known as transcriptional noise. Gene expression is influenced by trans-acting factors and cis-acting regulatory elements, and it is known that some sequence elements in promoters

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