Friday, May 18, 2012

Transcriptional Dominance of Pax7 in Adult Myogenesis Is Due to High-Affinity Recognition of Homeodomain Motifs

Transcriptional Dominance of Pax7 in Adult Myogenesis Is Due to High-Affinity Recognition of Homeodomain Motifs: Vahab D. Soleimani, Vincent G. Punch, Yoh-ichi Kawabe, Andrew E. Jones, Gareth A. Palidwor, Christopher J. Porter, Joe W. Cross, Jaime J. Carvajal, Christel E.M. Kockx, Wilfred F.J. van IJcken, Theodore J. Perkins, Peter W.J. Rigby, Frank Grosveld, Michael A. Rudnicki. Pax3 and Pax7 regulate stem cell function in skeletal myogenesis. However, molecular insight into their distinct roles has remained elusive. Using gene expression data combined with genome-wide bi....

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