Combinatorial temporal patterning in progenitors expands neural diversity

Combinatorial temporal patterning in progenitors expands neural diversity:
Combinatorial temporal patterning in progenitors expands neural diversity

Nature 498, 7455 (2013). doi:10.1038/nature12266

Authors: Omer Ali Bayraktar & Chris Q. Doe

Human outer subventricular zone (OSVZ) neural progenitors and Drosophila type II neuroblasts both generate intermediate neural progenitors (INPs) that populate the adult cerebral cortex or central complex, respectively. It is unknown whether INPs simply expand or also diversify neural cell types. Here we show that